POLR1C antibody

Catalog Number:

38120

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O15160
NCBI Gene ID: 9533

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Recombinant Protein of human POLR1C.

Purification:

Antibodies were purified by affinity purification using immunogen.

Specificity/Sensitivity:

The antibody detects endogenous level of total POLR1C antibody.

Applications:

WB,IHC,IF

Background:

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively. RPAC1 is part of the Pol core element with the central large cleft and probably a clamp element that moves to open and close the cleft. Rush,J., Nat. Biotechnol. 23 (1), 94-101 (2005) Hirschler-Laszkiewicz,I., J. Biol. Chem. 278 (21), 18953-18959 (2003) Dammann,R., Biochim. Biophys. Acta 1396 (2), 153-157 (1998) Seither,P., Chromosoma 106 (4), 216-225 (1997)

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

Datasheet PDF