SIK1 Antibody

Catalog Number:

37961

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P57059
NCBI Gene ID: 150094
Gene Accssion: NP_775490/P57059

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human salt-inducible kinase 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SIK1 protein.

Applications:

IHC

Background:

SIK1 (salt-inducible kinase 1), also known as SNF1LK or MSK, is a 783 amino acid protein that contains one UBA domain and one protein kinase domain and belongs to the Ser/Thr protein kinase family. Localized to both the nucleus and the cytoplasm, SIK1 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation. Additionally, SIK1 has a potential role in regulation of the G2/M cell cycle transition, as well as in inhibitory control of CREB protein function.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF