SLC39A3 Antibody

Catalog Number:

37941

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BRY0
NCBI Gene ID: 29985
Gene Accssion: NP_653165/Q9BRY0

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 39 (zinc transporter), member 3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SLC39A3 protein.

Applications:

IHC

Background:

SLC39A3 (solute carrier family 39, member 2), is a 314 amino acid acid multi-pass membrane protein that localizes to the cell membrane and belongs to the ZIP family of zinc transporters. Two isoforms of ZIP3 exist as a result of alternative splicing events. ZIP3 is involved in translocation of extracellular zinc into a variety of cell types. Tumorigenic prostate epithelial cells contain less intracellular zinc than non-tumorigenic prostate epithelial cells. Loss of the ability to maintain zinc accumulation may be caused by the decrease in the ZIP1 protein expression and the intracellular redistribution of ZIP3.

References:

appl_detail:

Immunohistochemistry: 1:20-1:100

Datasheet PDF