SLC25A20 Antibody

Catalog Number:

37934

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O43772
NCBI Gene ID: 788
Gene Accssion: NP_000378/O43772

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human solute carrier family 25 (carnitine/acylcarnitine translocase), member 20

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SLC25A20 protein.

Applications:

IHC

Background:

This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF