SCN1B Antibody

Catalog Number:

37898

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q07699
NCBI Gene ID: 6324
Gene Accssion: NP_001028/Q07699

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human sodium channel, voltage-gated, type I, beta subunit

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SCN1B protein.

Applications:

IHC

Background:

Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF