TNFRSF11A Antibody

Catalog Number:

37860

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9Y6Q6
NCBI Gene ID: 8792
Gene Accssion: NP_001257880/Q9Y6Q6

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TNFRSF11A protein.

Applications:

WB

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF