PIK3CB Antibody

Catalog Number:

37828

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P42338
NCBI Gene ID: 5291
Gene Accssion: NP_006210/P42338

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PIK3CB protein.

Applications:

IHC

Background:

This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF