PER2 Antibody

Catalog Number:

37814

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O15055
NCBI Gene ID: 8864
Gene Accssion: NP_073728/O15055

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human period circadian clock 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PER2 protein.

Applications:

IHC

Background:

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic Nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.

References:

appl_detail:

Immunohistochemistry: 1:100-1:300

Datasheet PDF