PDE5A Antibody

Catalog Number:

37810

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O76074
NCBI Gene ID: 8654
Gene Accssion: NP_001074/O76074

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human phosphodiesterase 5A, cGMP-specific

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PDE5A protein.

Applications:

WB IHC

Background:

This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.?

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:300

Datasheet PDF