MED12 Antibody

Catalog Number:

37786

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q93074
NCBI Gene ID: 9968
Gene Accssion: NP_005111

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human mediator complex subunit 12

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MED12 protein.

Applications:

IHC

Background:

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along with MED13, CDK8 kinase, and cyclin C.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF