SH2D3A Antibody

Catalog Number:

37779

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BRG2
NCBI Gene ID: 10045
Gene Accssion: NP_005481

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human SH2 domain containing 3A

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SH2D3A protein.

Applications:

IHC

Background:

SH2D3A (SH2 domain containing 3A), also known as novel SH2-containing protein 1, is a 576 amino acid protein that is thought to play a role in JNK activation. SH2D3A interacts with p130 Cas and is found at low levels in fetal kidney, fetal lung, placenta, adult pancreas, kidney and lung. Subject to post-translational phosphorylation on multiple tyrosine residues, SH2D3A contains one Src homology 2 (SH2) domain. SH2 domains bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF