NLRP10 Antibody

Catalog Number:

37767

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q86W26
NCBI Gene ID: 338322
Gene Accssion: NP_789791

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human NLR family, pyrin domain containing 10

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NLRP10 protein.

Applications:

WB

Background:

Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF