FGF2 Antibody

Catalog Number:

36769

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P09038
NCBI Gene ID: 2247
Gene Accssion: NP_001997

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human Fibroblast growth factor 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FGF2 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

References:

appl_detail:

Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:100-1:500

Datasheet PDF