ASCL1 Antibody

Catalog Number:

36763

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P50553
NCBI Gene ID: 429
Gene Accssion: NP_004307

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human achaete-scute complex homolog 1 (Drosophila)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ASCL1 protein.

Applications:

IHC

Background:

This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF