NUMB Antibody

Catalog Number:

36663

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P49757
NCBI Gene ID: 8650
Gene Accssion: BC020788/P49757

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the N terminal of human numb homolog (Drosophila)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NUMB protein.

Applications:

WB

Background:

The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF