HMGCL Antibody

Catalog Number:

36521

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P35914
NCBI Gene ID: 3155
Gene Accssion: BC010570

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human 3-hydroxymethyl-3-methylglutaryl-CoA lyase

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HMGCL protein.

Applications:

WB IHC

Background:

The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.?

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:50-1:200

Datasheet PDF