FAP Antibody

Catalog Number:

36465

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q12884
NCBI Gene ID: 2191
Gene Accssion: BC026250

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human fibroblast activation protein, alpha

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FAP protein.

Applications:

IHC

Background:

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF