EDA Antibody

Catalog Number:

36433

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q92838
NCBI Gene ID: 1896
Gene Accssion: BC126143

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human ectodysplasin A

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EDA protein.

Applications:

IHC

Background:

The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF