CHAC1 Antibody

Catalog Number:

36347

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9BUX1
NCBI Gene ID: 79094
Gene Accssion: BC001683

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CHAC1 protein.

Applications:

IHC

Background:

CHAC1 (ChaC, cation transport regulator homolog 1 (E. coli)) is a 264 amino acid cytoplasmic protein that belongs to the ChaC family. Induced by chemical activators of the unfolded protein response (UPR) pathway, including DTT, tunicamycin and thapsigargin, CHAC1 is a pro-apoptotic member of this pathway and may mediate the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. Overexpression of CHAC1 may lead to an increase in apoptosis, while suppression of CHAC1 results in subdued apoptosis.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF