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Catalog Number: |
36343 |
| other_names: | LAP; CPAP; LIP1; BM032; MCPH6; SASS4; SCKL4; Sas-4; CENP-J |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: Q9HC77 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Fusion protein corresponding to residues near the C terminal of human centromere protein J |
Purification: |
Antigen affinity purification. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total CENPJ protein. |
Applications: |
IHC |
Background: |
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein.? |
References: |
|
appl_detail: |
Immunohistochemistry: 1:25-1:100 |
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