THOC7 Antibody

Catalog Number:

36221

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q6I9Y2
NCBI Gene ID: 80145
Gene Accssion: BC065012

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total THOC7 protein.

Applications:

WB IHC

Background:

NIF3L1 BP1 (Ngg1-interacting factor 3-like 1 binding protein 1), also known as THOC7 (THO complex subunit 7 homolog), fSAP24 or hTREX30, is a 204 amino acid cytoplasmic and nuclear protein that belongs to the THOC7 family and interacts with NIF3L1. NIF3L1 BP1 is a component of the THO/TREX complex that is recruited to transcribed genes and travels along with RNA polymerase II (Pol II) during elongation, coupling Pol II with RNA splicing and export factors. The THO/TREX complex also plays a role in the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The gene that encodes NIF3L1 BP1 maps to human chromosome 3p14.1.?

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:25-1:100

Datasheet PDF