1-832-868-1888
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Catalog Number: |
36625 |
| other_names: | MTP18; HSPC242 |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: Q9UDX5 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Fusion protein corresponding to a region derived from internal residues of human mitochondrial fission process 1 |
Purification: |
Antigen affinity purification. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total MTFP1 protein. |
Applications: |
WB IHC |
Background: |
MTP18 (mitochondrial 18 kDa protein), also known as HSPC242, is a 166 amino acid protein essential for cell viability. MTP18 may also have a role in maintaining the integrity of the mitochondrial network. Localized to the mitochonrion, expression of MTP18 is regulated by the PI 3-kinase pathway. Loss of function of MTP18 results in the release of cytochrome c, which subsequently activates the caspase cascade and leads to apoptosis. |
References: |
|
appl_detail: |
Western blotting: 1:500-1:2000 |
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