STAMBP Antibody

Catalog Number:

36099

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O95630
NCBI Gene ID: 10617
Gene Accssion: BC065574

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human STAM binding protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total STAMBP protein.

Applications:

IHC

Background:

Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF