AGBL2 Antibody

Catalog Number:

36058

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q5U5Z8
NCBI Gene ID: 79841
Gene Accssion: BC028200

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AGBL2 protein.

Applications:

IHC

Background:

Metallocarboxypeptidase that may play a role in the processing of tubulin. Knockdown of AGBL2 results in a failure of the cell to detyrosinate the C-terminal EEY region of α-tubulin and indicates that, it is a candidate for the long sought after tubulin tyrosine carboxypeptidase important in regulation of microtubule dynamics. RARRES1, its interacting partners AGBL2, Eg5/KIF11, another EEY bearing protein (EB1), and the microtubule tyrosination cycle are important in tumorigenesis and identify a novel area for therapeutic intervention.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF