1-832-868-1888
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Catalog Number: |
35971 |
| other_names: | RNF84; MGC:39780 |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: O00463 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Fusion protein corresponding to a region derived from internal residues of human TNF receptor-associated factor 5 |
Purification: |
Antigen affinity purification. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total TRAF5 protein. |
Applications: |
WB IHC |
Background: |
The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized. |
References: |
|
appl_detail: |
Western blotting: 1:500-1:2000 |
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