TPO Antibody

Catalog Number:

35966

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P07202
NCBI Gene ID: 7173
Gene Accssion: BC063107

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TPO protein.

Applications:

IHC

Background:

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF