CDH3 Antibody

Catalog Number:

35871

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P22223
NCBI Gene ID: 1001
Gene Accssion: BC014462

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human cadherin 3, type 1, P-cadherin (placental)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CDH3 protein.

Applications:

WB IHC

Background:

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:5-1:20

Datasheet PDF