PARD6A Antibody

Catalog Number:

35868

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NPB6
NCBI Gene ID: 50855
Gene Accssion: BC015626

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human par-6 family cell polarity regulator alpha

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PARD6A protein.

Applications:

IHC

Background:

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF