NRN1 Antibody

Catalog Number:

35833

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NPD7
NCBI Gene ID: 51299
Gene Accssion: BC002683

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human neuritin 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NRN1 protein.

Applications:

IHC

Background:

This gene encodes a member of the neuritin family, and is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of this gene can be induced by neural activity and neurotrophins. The encoded protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. The encoded protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis. Overexpression of the encoded protein may be associated with astrocytoma progression. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF