ECE2 Antibody

Catalog Number:

35719

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60344
NCBI Gene ID: 9718
Gene Accssion: BC005835

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human endothelin converting enzyme 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ECE2 protein.

Applications:

IHC

Background:

Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family. It converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF