DKK2 Antibody

Catalog Number:

35714

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UBU2
NCBI Gene ID: 27123
Gene Accssion: BC126328

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human dickkopf WNT signaling pathway inhibitor 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DKK2 protein.

Applications:

WB

Background:

This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF