CYP1B1 Antibody

Catalog Number:

35705

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q16678
NCBI Gene ID: 1545
Gene Accssion: BC012049

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human Cytochrome P450, family 1, subfamily B, polypeptide 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CYP1B1 protein.

Applications:

WB

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF