CRTAM Antibody

Catalog Number:

35697

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O95727
NCBI Gene ID: 56253
Gene Accssion: BC070266

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human cytotoxic and regulatory T cell molecule

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CRTAM protein.

Applications:

IHC

Background:

The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF