1-832-868-1888
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Catalog Number: |
35673 |
| other_names: | BGR; CANDF4; DECTIN1; CLECSF12 |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: Q9BXN2 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Full length fusion protein |
Purification: |
Antigen affinity purification. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total CLEC7A protein. |
Applications: |
WB IHC |
Background: |
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. |
References: |
|
appl_detail: |
Western blotting: 1:500-1:2000 |
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