CTSE Antibody

Catalog Number:

35666

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P14091
NCBI Gene ID: 1510
Gene Accssion: BC042537

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human Cathepsin E

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CTSE protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.

References:

appl_detail:

Western blotting: 1:100-1:500
Immunohistochemistry: 1:25-1:100

Datasheet PDF