CAPN7 Antibody

Catalog Number:

35658

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9Y6W3
NCBI Gene ID: 23473
Gene Accssion: BC056202

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human calpain 7

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CAPN7 protein.

Applications:

IHC

Background:

Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity.?

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF