BACE1 Antibody

Catalog Number:

35650

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P56817
NCBI Gene ID: 23621
Gene Accssion: BC065492

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human beta-site APP-cleaving enzyme 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total BACE1 protein.

Applications:

WB

Background:

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF