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KRT4 Antibody

Catalog Number:

35626
other_names: K4; CK4; CK-4; CYK4

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P19013
NCBI Gene ID: 3851
Gene Accssion: BC042174

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human keratin 4

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KRT4 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:5-1:20

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