AARS2 Antibody

Catalog Number:

35611

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q5JTZ9
NCBI Gene ID: 57505
Gene Accssion: BC131728

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human Alanyl-tRNA synthetase 2, mitochondrial

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AARS2 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:50-1:200

Datasheet PDF