IL1RAP Antibody

Catalog Number:

35605

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NPH3
NCBI Gene ID: 3556
Gene Accssion: BC053621

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human Interleukin-1 receptor accessory protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total IL1RAP protein.

Applications:

IHC

Background:

Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.

References:

appl_detail:

Immunohistochemistry: 1:10-1:50

Datasheet PDF