BCOR Antibody

Catalog Number:

35594

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q6W2J9
NCBI Gene ID: 54880
Gene Accssion: BC063536

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human BCL6 corepressor

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total BCOR protein.

Applications:

WB

Background:

The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF