TONSL Antibody

Catalog Number:

35590

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q96HA7
NCBI Gene ID: 4796
Gene Accssion: BC008782

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human tonsoku-like, DNA repair protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TONSL protein.

Applications:

IHC

Background:

The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.?

References:

appl_detail:

Immunohistochemistry: 1:100-1:300

Datasheet PDF