COX6B1 Antibody

Catalog Number:

35582

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P14854
NCBI Gene ID: 1340
Gene Accssion: BC001015

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human Cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total COX6B1 protein.

Applications:

WB IHC

Background:

Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.

References:

appl_detail:

Western blotting: 1:1000-1:5000
Immunohistochemistry: 1:25-1:100

Datasheet PDF