TLR7 Antibody

Catalog Number:

35578

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9NYK1
NCBI Gene ID: 51284
Gene Accssion: BC033651

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human Toll-like receptor 7

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TLR7 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.

References:

appl_detail:

Immunohistochemistry: 1:10-1:50

Datasheet PDF