1-832-868-1888
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Catalog Number: |
35563 |
| other_names: | 15-LOX-2 |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#: O15296 |
Form of Antibody: |
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Storage/Stability: |
|
Immunogen: |
Fusion protein corresponding to a region derived from internal residues of human arachidonate 15-lipoxygenase, type B |
Purification: |
Antigen affinity purification. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total ALOX15B protein. |
Applications: |
IHC |
Background: |
This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. |
References: |
|
appl_detail: |
Immunohistochemistry: 1:15-1:50 |
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