NRGN Antibody

Catalog Number:

35545

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q92686
NCBI Gene ID: 4900
Gene Accssion: BC002835

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NRGN protein.

Applications:

WB

Background:

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF