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Prickle-like protein 2 Antibody

Catalog Number:

35479
other_names: DKFZp686D143 antibody; DKFZp686H1748 antibody; DKFZp686M031 antibody; PRICKLE2 antibody; prickle-like protein 2 antibody; prickle homolog 2 (Drosophila) antibody

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q7Z3G6;
NCBI Gene#:166336

Form of Antibody:

Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant fragment corresponding to a region within amino acids 5 and 281 of Prickle-like protein 2.

Purification:

Antibodies were purified by antigen-affinity chromatography.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Prickle-like protein 2 protein.

Applications:

WB

Background:

PRICKLE2 Defects in PRICKLE2 are the cause of progressive myoclonic epilepsy type 5 (EPM5). EPM5 is a neurodegenerative disorder characterized by myoclonic seizures and variable neurologic symptoms including cognitive decline and persistent movement abnormalities. Belongs to the prickle / espinas / testin family.

References:

appl_detail:

Datasheet PDF

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