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Catalog Number: |
35440 |
| other_names: | EIEE10 antibody; MCSZ antibody; PNK antibody; PNKP antibody; DNA 5'-kinase/3'-phosphatase antibody; Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP) antibody; bifunctional polynucleotide phosphatase/kinase antibody; polynucleotide kinase 3'-phosph |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:Q96T60; |
Form of Antibody: |
Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage/Stability: |
|
Immunogen: |
Recombinant fragment corresponding to a region within amino acids 1 and 273 of PNK. |
Purification: |
Antibodies were purified by antigen-affinity chromatography. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total PNK protein. |
Applications: |
WB |
Background: |
This locus represents a gene involved in DNA repair. In response to ionizing radiation or oxidative damage, the protein encoded by this locus catalyzes 5' phosphorylation and 3' dephosphorylation of nucleic acids. Mutations at this locus have been associated with microcephaly, seizures, and developmental delay. |
References: |
|
appl_detail: |
Western blotting: 1:500-1:3000 |
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