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Catalog Number: |
35418 |
| other_names: | UBP-M antibody; USP16 antibody; ubiquitin thiolesterase 16 antibody; ubiquitin-specific processing protease 16 antibody; deubiquitinating enzyme 16 antibody; ubiquitin specific protease 16 antibody; ubiquitin thioesterase 16 antibody; ubiquitin-processing |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:Q9Y5T5; |
Form of Antibody: |
Rabbit IgG in 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage/Stability: |
|
Immunogen: |
Synthetic peptide corresponding to a region within amino acids 1 and 45 of USP16. |
Purification: |
Antibodies were purified by antigen-affinity chromatography. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total USP16 protein. |
Applications: |
WB |
Background: |
This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
References: |
|
appl_detail: |
Western blotting: 1:500-1:3000 |
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