Tyrosine Hydroxylase Antibody

Catalog Number:

35392

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P07101;
NCBI Gene#:7054

Form of Antibody:

Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant fragment corresponding to a region within amino acids 1 and 270 of Tyrosine Hydroxylase.

Purification:

Antibodies were purified by antigen-affinity chromatography.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Tyrosine Hydroxylase protein.

Applications:

IF WB

Background:

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq]

References:

appl_detail:

Western blotting: 1:500-1:3000
Immunofluorescence: 1:100-1:1000

Datasheet PDF